Skip to main content
Journal of Pharmaceutical Analysis logoLink to Journal of Pharmaceutical Analysis
. 2022 Jun 2;12(4):698–700. doi: 10.1016/j.jpha.2022.05.002

Corrigendum to “The effective transfection of a low dose of negatively charged drug-loaded DNA-nanocarriers into cancer cells via scavenger receptors”[Journal of Pharmaceutical Analysis volume 11 (2021) 174–182]

Mirza Muhammad Faran Ashraf Baig a,b,c,, Chengfei Zhang a, Muhammad Furqan Akhtar d, Ammara Saleem e, Jahanzeb Mudassir c
PMCID: PMC9463485  PMID: 36105158

Fig. 4.

Image 1

AFM and confocal characterization of DNA-NWs. (A) AFM imaging of DNA-NWs. (B) Confocal imaging of FITC-tagged CPT-loaded DNA-NWs.

Fig. 6.

Image 2

Biocompatibility and cytotoxicity assay of blank and CPT-loaded DNA-NW. MTT assay of (A) biocompatibility of blank DNA-NWs and (B) cytotoxicity of CPT-loaded DNA-NWs compared with equivalent concentrations of free CPT solution. (C) Flow cytometry assessment of the biocompatibility of blank solution, DNA-NW solution, and the cytotoxicity of CPT-loaded DNA-NW.

Fig. 7.

Image 3

Surface binding of DNA-NW loaded with FITC-tagged CPT to the human liver cancer cell line (HepG2) compared with the control cell line (CHSE-214) derived from the salmon embryo after a 30 min interval. (A) As HepG2 cells are rich in scavenger receptors, DNA-NW binds the cell surfaces followed by gradual internalization into the cells and release of FITC-tagged CPT into the cytoplasm. (B) As CHSE-214 cells lack scavenger receptors, DNA-NW could not bind these cells effectively, resulting in inferior cell internalization.

The authors regret to inform that Figs. 4, 6, and 7 in the original article were wrongly selected. The corrected figures appear below:

The authors would like to apologize for any inconvenience caused.


Articles from Journal of Pharmaceutical Analysis are provided here courtesy of Xi'an Jiaotong University

RESOURCES