Table 1.
Human-derived E. coli isolated from intestinal biopsies are genetically tractable
| Metadata |
Antibiotic MIC (mg/mL) |
Transformation (% efficiency) |
Conjugation |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Strain | Host species | Tissue | Cm | Kan | Carb | Small plasmid (4.4 kb) | Medium plasmid (35 kb) | Large plasmid (70 kb) | Efficiency (or limit of detection) |
|
| |||||||||
| EcAZ-1 | mouse (C57BL6) | feces | 5 | 6.25 | 25 | 4.25 | 4.51E–4 | 6.60E–5 | 5.98E–3 |
| AZ-61 | human-2 | rectum | 5 | 6.25 | 50 | 0.067 | 1.97E–4 | 1.99E–5 | 1.31E–5 |
| AZ-116 | human-4 | ileum | 10 | 6.25 | resistant | - | 2.58E–6 | 2.42E–5 | 2.58E–3 |
| AZ-120 | cecum | 5 | 6.25 | 25 | 0.23 | 1.18E–6 | 1.44E–5 | 5.13E–3 | |
Abbreviations: Cm, chloramphenicol; Kan, kanamycin; Carb, carbenicillin; see also Figure S5.