Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The number of different sequences introduced in each CDR position of light and heavy chain. Theoretical diversity is calculated by the combinatorial potential of the CDRs and the reported number of transformants corresponds to the yeast display libraries created.
| Family | Region | CDRs | Library | Diversity | Transformants |
|---|---|---|---|---|---|
| Vλ3 | LCDR1 | 1,155 | L1L2 | 498,960 | 1.26x107 |
| LCDR2 | 432 | ||||
| Vλ | LCDR3 | 166,196 | L3 | 166,196 | 1.23x107 |
| VH3 | HCDR1 | 9,874 | H1H2 | 31,685,666 | 7.4x107 |
| HCDR2 | 3,209 |
