TABLE 1.

Suggested Management of HA in FLC

Management Options	Commonly Used Measures
Outpatient management	Oral nitrogen scavenger (e.g., sodium phenylbutyrate, glycerol phenylbutyrate) and l-citrulline
Emergent cases	CVVH; i.v. sodium benzoate and sodium phenylacetate, arginine hydrochloride, and D10-based fluids
Refractory to medical therapy	Consideration of debulking surgery to reduce FLC tumor volume, in conjunction with medical management, when feasible, and consistent with the overall goals of care