Table 2. . Summary of miRNAs from predicted miRNA–mRNA expression pairs (n = 20).
miRNA | mRNA pair | Correlation coefficient | miRNA role |
---|---|---|---|
miR-765 | RAB5A | ‐0.590 | Apoptosis and suppressed cell proliferation |
CBX5 | ‐0.580 | ||
RBM47 | ‐0.535 | ||
SERPINB9 | ‐0.510 | ||
IQGAP1 | ‐0.624 | ||
SDCBP | ‐0.492 | ||
GDPD5 | ‐0.473 | ||
miR-296-3p | IQGAP1 | ‐0.615 | Inflammation and cell invasion |
RC3H1 | ‐0.497 | ||
SERPINB9 | ‐0.495 | ||
miR-885-3p | RC3H1 | ‐0.456 | Inflammation and enhanced NF-κB signaling |
SERPINB9 | ‐0.490 | ||
TMEM192 | ‐0.489 | ||
miR-1207-5p | CBX5 | ‐0.458 | Inflammation |
miR-671-5p | RAB5A | ‐0.453 | Suppressed NF-κB and neuroinflammation |
miR-920 | RC3H1 | ‐0.453 | Production of proinflammatory cytokines |
miR-936 | SDCBP | ‐0.428 | Apoptosis |
RC3H1 | ‐0.447 | ||
miR-877-5p | IQGAP1 | ‐0.439 | Reduced release of TNF-α, IL-1B and IL-6; suppressed inflammatory response; and apoptosis |
miR-202-3p | RBM47 | ‐0.425 | Reduced inflammatory factor expression, angiogenesis and cancer cell apoptosis |
miRNAs chosen represent those observed within the first 20 pairs, based on correlation coefficient. Correlation between variance stabilized counts of miRNAs and mRNAs was calculated using the Pearson correlation coefficient. All expression pairs show p < 0.1.