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. 2022 Sep 19;10(9):2328. doi: 10.3390/biomedicines10092328

Figure 3.

Figure 3

Food intake and body changes in response to GC excess. (a) Daily food intake per week; (b) average 28 days daily food intake; (c) feed efficiency; (d) hypothalamic gene expression of Npy, Agrp, Pomc, Cartpt, and Lepr; (e) body weight change; (f) nasal–anal length; (g) gastrocnemius—G, soleus—S, and extensor digitorum longus—E muscle mass; and (h) tibia bone weight, length, and circumference of control (CT), and glucocorticoid-treated (GC) rats. Data are mean ± SEM of 13 (CT) and 17 (GC) rats/samples (a–c,e–h), and 6 (CT) and 6 (GC) samples (d). * p < 0.05; ** p < 0.01; *** p < 0.001 and **** p < 0.0001 vs. CT (unpaired Student t-test; Mann–Whitney test in h-length). (f) **** p < 0.0001 (Repeated Measures Two-Way ANOVA with Bonferroni’s post hoc test).