Table 1.
Single-cell mRNA expression levels of TRP channels in the respiratory tract.
| Cell Type | TRP Channel |
nTPM |
|---|---|---|
| AT2 cells | TRPC6 | 2.6 |
| TRPM2 | 0.5 | |
| B cells | TRPM2 | 2.0 |
| TRPV2 | 11.1 | |
| TRPV4 | 0.7 | |
| Basal cells | TRPV4 | 17.1 |
| Ciliated cells | TRPC6 | 0.8 |
| TRPV2 | 0.8 | |
| TRPV4 | 28.2 | |
| Club Cells | TRPC6 | 10.5 |
| TRPV2 | 0.6 | |
| TRPV4 | 12.0 | |
| Endothelial cells | TRPC6 | 1.6 |
| TRPM2 | 2.7 | |
| TRPV2 | 12.3 | |
| TRPV4 | 1.4 | |
| Fibroblasts | TRPA1 | 8.1 |
| TRPC6 | 3.1 | |
| TRPM2 | 0.5 | |
| TRPV2 | 11.0 | |
| TRPV4 | 1.2 | |
| Macrophages | TRPC6 | 1.8 |
| TRPM2 | 16.7 | |
| TRPV2 | 28.7 | |
| TRPV4 | 2.6 | |
| Smooth muscle cells | TRPA1 | 0.8 |
| TRPC6 | 20.2 | |
| TRPM2 | 0.4 | |
| TRPV2 | 23.6 | |
| TRPV4 | 1.1 | |
| T cells | TRPC6 | 0.1 |
| TRPM2 | 4.2 | |
| TRPV2 | 26.8 | |
| TRPV4 | 0.3 |
nTPM (high =>10), normalized transcripts per million from the Human Protein Atlas. (www.proteinatlas.org, accessed date: 9 September 2022).