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International Journal of Molecular Sciences logoLink to International Journal of Molecular Sciences
. 2022 Sep 6;23(18):10230. doi: 10.3390/ijms231810230

Correction: Funk et al. Criticality of Surface Characteristics of Intravenous Iron-Carbohydrate Nanoparticle Complexes: Implications for Pharmacokinetics and Pharmacodynamics. Int. J. Mol. Sci. 2022, 23, 2140

Felix Funk 1, Beat Flühmann 1, Amy E Barton 1,*
PMCID: PMC9499350  PMID: 36142898

The authors wish to make the following corrections to this paper [1]:

In the original publication, there were wrong reference citations in paragraph 7 of Section 2.2 and Table 4 as published.

In Section 2.2, paragraph 7, “Ferumoxytol contains 30 mg of iron/mL. The complex is an iron oxide coated with polyglucose sorbitol carboxymethylether. The chemical formula of ferumoxytol is Fe5874O8752-C11719H18682O9933Na414 [24]” should be replaced with “Ferumoxytol contains 30 mg of iron/mL. The complex is an iron oxide coated with polyglucose sorbitol carboxymethylether [25]. The chemical formula of ferumoxytol is Fe5874O8752-C11719H18682O9933Na414 [26]”.

In Table 4, the reference numbers did not correspond with the correct numbers in the reference list. The corrected Table 4 appears below:

Product Molecular Weight (kDa) Particle Size (nm)[39] Zeta Potential (mV)[39] Crystalline Structure Reduction Potential (mV) °[25] Reduction Kinetics k(Θ) × 103 (min−1)
Θ = 0.1/0.5/0.8[25]
Blocking Temperature (K)
[25,40]
Iron sucrose 34–60 [17,41]
42–44 [25]
252 [42]
140 [39]
8.3 (PDI 0.192) pH 7.43: −26.20
pH 11.03 *: −28.15
2-line ferrihydrite [39]
Ferrihydrite and lepidocrocite [41]
Akageneite [33]
2-line ferrihydrite-like [40]
No clear identification [25]
−494 107/89/117 § 55
Sodium ferric gluconate 289–440 [18]
37.5 [9]
200 [42]
164 [39]
8.6 (PDI 0.244) pH 7.4: −29.70
pH 8.36 *: −29.10
2-line ferrihydrite ([39]
Ferrihydrite and lepidocrocite [41]
Akaganeite [33]
nd nd nd
Iron dextran 165 [20]
165 [39]
12.2 (PDI 0.149) pH 6.4 *: −15.30
pH 7.31: −17.25
Akageneite [39,41] nd nd nd
Ferric derisomaltose 155[22]
63–69 [25]
150 [39]
9.9 (PDI 0.182) pH 6.3 *: −22.0
pH 7.35: −21.05
Akaganeite [25,39,41] −338/−508 21/41/63 56
Ferric carboxymaltose ≈ 150 [24]
145–155 [25]
233 [39]
23.1 (PDI 0.07) pH 5.36: 3.68
pH 7.26: −8.52
Akaganeite [25,39,41] −333 18/35/55 114
Ferumoxytol 750 [26]
172–188 [25]
731 [42]
276 [39]
23.6 (PDI 0.143) pH 6.6: −43.20
pH 7.36: −30.55
Magnetite/Maghemite [39]
Magnetite [41]
Maghemite [25]
−245/−768 36/67/98 73

The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

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Reference

  • 1.Funk F., Flühmann B., Barton A.E. Criticality of surface characteristics of intravenous iron-carbohydrate nanoparticle complexes: Implications for pharmacokinetics and pharmacodynamics. Int. J. Mol. Sci. 2022;23:2140. doi: 10.3390/ijms23042140. [DOI] [PMC free article] [PubMed] [Google Scholar]

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