Table 4.
Effect of Rumex hastatus crude extract (Rh.Cr) and fractions: n-hexane (Rh.n-Hex), ethyl acetate (Rh.ETAC), aqueous (Rh.Aq), rutin and atropine against castor-oil induced fluid accumulation in mice.
| Treatment (mg/kg) | % Inhibition |
|---|---|
| Saline (10 mL/kg) | 89.7 |
| Castor-oil (10 mL/kg) | 126.8 ### |
| Rh.Cr (50 mg/kg) + Castor-oil (10 mL/kg) | 119 * |
| Rh.Cr (100 mg/kg) + Castor-oil (10 mL/kg) | 105 ** |
| Rh.Cr (300 mg/kg) + Castor-oil (10 mL/kg) | 85 *** |
| Rh.nHex (50 mg/kg) + Castor-oil (10 mL/kg) | 120.6 |
| Rh.nHex (100 mg/kg) + Castor-oil (10 mL/kg) | 110 ** |
| Rh.nHex (300 mg/kg) + Castor-oil (10 mL/kg) | 92.8 *** |
| Rh.ETAC (50 mg/kg) + Castor-oil (10 mL/kg) | 118 * |
| Rh.ETAC (100 mg/kg) + Castor-oil (10 mL/kg) | 99 *** |
| Rh.ETAC (300 mg/kg) + Castor-oil (10 mL/kg) | 78 *** |
| Rh.Aq (50 mg/kg) + Castor-oil (10 mL/kg) | 124 |
| Rh.Aq (100 mg/kg) + Castor-oil (10 mL/kg) | 122 |
| Rh.Aq (300 mg/kg) + Castor-oil (10 mL/kg) | 118 * |
| Rutin (50 mg/kg) + Castor-oil (10 mL/kg) | 109 ** |
| Rutin (100 mg/kg) + Castor-oil (10 mL/kg) | 85 *** |
| Rutin (200 mg/kg) + Castor-oil (10 mL/kg) | 75 *** |
| Atropine (0.1 mg/kg) + Castor-oil (10 mL/kg) | 74.10 *** |
Values expressed as mean ± SEM (n = 5). One-way ANOVA with post-hoc Tukey’s test. ### p < 0.001 vs. saline group, *p < 0.05, ** p < 0.01, *** p < 0.001 vs. castor oil group.