Figure 1.

Hemolytic activity of the cationic antimicrobial peptides (CAMPs) pept_1, pept_2, pept_3, pept_4 and pept_5. Solid lines—erythrocytes were added to the same volume of PBS containing the peptide; dashed lines—erythrocytes were added to the same volume of PBS containing the peptide and autologous plasma. Peptide concentrations indicated on the X-axis are final concentrations in the cell-containing samples, with a final plasma dilution of 1:10. Hemolysis was assayed after 0.5 h of incubation at 37 °C. Cells with Triton X-100 served as a positive control, which was set to 100%. Data shown are mean ± SD from three independent experiments using blood from three subjects, with triplicate samples in each experiment.