Table 1.

Survival analysis according to time-varying MRD positivity (BM and PB)

	TTP risk based on punctual MRD determination by nested and RQ-PCR in BM and PB samples
	BM			PB
TTP	HR	95% CI	P value	HR	95% CI	P value
Nested PCR	2.19	(1.10-4.35)	.025	1.83	(1.14-2.94)	.013
RQ-PCR	3.75	(2.37-5.93)	<.001	2.33	(1.46-3.70)	<.001

Analyses were performed with Cox proportional-hazard models on subjects with available information for both nested and RQ-PCR (166 subjects with 782 determinations for BM and 166 subjects with 761 determinations for PB).