Table 5.

Coagulation profile among studied COVID-19 patients

	None-severe group (n = 86)	Severe group (n = 20)	P value
INR	1.03 ± 0.15	1.34 ± 0.63	< 0.001
Prothrombin time (s)	12.98 ± 4.06	13.23 ± 2.36	0.79
Prothrombin concentration (%)	96.84 ± 31.89	90.64 ± 29.55	0.43
aPPT (s)	32.99 ± 5.75	45.03 ± 27.77	< 0.001
Fibrinogen (g/l)	3.55 ± 1.42	4.20 ± 1.68	0.08
d-Dimer (mg/l)	10.45 ± 2.34	16.45 ± 5.45	< 0.001
Factor VIII (%)	134.53 ± 79.65	216.33 ± 110.51	< 0.001
von Willebrand factor (%)	219.26 ± 104.87	327.13 ± 60.04	< 0.001
Protein C (%)	113.47 ± 35.78	105.14 ± 63.43	0.42
Protein S (%)	59.49 ± 31.19	49.13 ± 23.47	0.20
Antithrombin III (%)	109.53 ± 18.39	95.24 ± 29.63	< 0.001
Lupus anticoagulant-1 (s)	58.10 ± 13.37	85.33 ± 33.45	< 0.001
Lupus anticoagulant-2 (s)	46.98 ± 7.01	65.10 ± 24.11	< 0.001
LA-1/LA-2 ratio	1.22 ± 0.17	1.86 ± 0.25	< 0.001

Data expressed as mean (SD)

s second, INR international randomized ratio, aPPT activated partial thromboplastin time, LA lupus anticoagulant

P value was significant if  < 0.05