Table 5.
Univariate Cox proportional hazards regression analysis of progression-free survival (PFS) and overall survival (OS)
| Factor | PFS | OS | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | P | HR | 95%CI | P | |
| Gender | ||||||
| Female | 1 | 1 | ||||
| Male | 1.083 | 0.330-3.554 | 0.896 | 2.612 | 0.504-13.543 | 0.253 |
| Age | ||||||
| ≤ 55 y | 1 | 1 | ||||
| > 55 y | 1.318 | 0.401-4.330 | 0.649 | 2.188 | 0.488-9.806 | 0.306 |
| Primary tumor type | ||||||
| Non-pancreatic | 1 | 1 | ||||
| Pancreatic | 0.523 | 0.159-1.721 | 0.286 | 0.308 | 0.060-1.594 | 0.160 |
| Ki-67 index | ||||||
| ≤ 10% | 1 | |||||
| > 10% | 4.973 | 1.430-17.293 | 0.012 | 1.527 | 0.341-6.838 | 0.580 |
| Number of organs involved | ||||||
| ≤ 1 | 1 | 1 | ||||
| > 1 | 0.309 | 0.082-1.169 | 0.084 | 0.898 | 0.200-4.035 | 0.888 |
| Bone metastases | ||||||
| No | 1 | 1 | ||||
| Yes | 2.135 | 0.623-7.313 | 0.227 | 1.260 | 0.242-6.552 | 0.783 |
| Hepatic tumor burden | ||||||
| ≤ 50% | 1 | 1 | ||||
| > 50% | 1.183 | 0.360-3.892 | 0.782 | 1.680 | 0.375-7.524 | 0.498 |
| Surgery of primary tumor | ||||||
| No | 1 | 1 | ||||
| Yes | 1.773 | 0.513-6.120 | 0.365 | 2.335 | 0.447-12.199 | 0.315 |
| Chemotherapy | ||||||
| No | 1 | 1 | ||||
| Yes | 2.849 | 0.826-9.817 | 0.097 | 1.140 | 0.255-5.100 | 0.864 |