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Haemotoxylin and eosin, and p53, staining of (a,b) post-treatment biopsies and (c,d) Cytosponge™ samples taken from a patient who received chemoradiotherapy for oesophageal adenocarcinoma. The biopsy stains show no atypia and wild-type p53 staining. The Cytosponge™ samples show atypia and p53 overexpression, indicating high risk of residual/recurrent tumour.
