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. 2022 Sep 5;14(9):e28812. doi: 10.7759/cureus.28812

Figure 3. Effects of intravenous NMN administration on metabolic markers of liver, pancreas, heart, and kidney.

Figure 3

Levels of metabolic markers of the liver, pancreas, heart, and kidney were measured in plasma obtained from subjects before and at 0.5, 1, 2, 3, and 5 h after intravenous NMN administration. The effects of the intravenous NMN administration on liver metabolism were evaluated via (a) T-Bill, (b) I-Bill, (c) D-Bill, (d) AST, (e) ALT, (f) ALP, (g) γ-GT, (h) Ch-E, and (i) LD; pancreatic metabolism was evaluated based on (j) AMY; cardiac metabolism was observed based on (k) CK and (l) CK-MB; renal metabolism was evaluated based on (m) UN, (n) UA, (o) eGFR, and (p) CRE. The results are expressed as mean ± standard deviation (n = 10).

NMN: Nicotinamide mononucleotide; T-Bill: Total bilirubin; I-Bill: Indirect bilirubin; D-Bill: Direct bilirubin; AST: Aspartate transaminase; ALT: Alanine aminotransferase; ALP: Alanine phosphotransferase; γ-GT: Gamma-glutamyl transferase; LD: Lactate dehydrogenase; Ch-E: Cholinesterase; AMY: Amylase; CK: Creatine kinase; CK-MB: CK myocardial band; UN: Urea nitrogen; CRE: Creatinine; UA: Urinalysis; eGFR: Estimated glomerular filtration rate