Fever, COVID‐19 vaccination, and Brugada syndrome: Incidence and management—Correspondence

Dear Editor,

We would like to share ideas on “Fever following COVID‐19 vaccination in subjects with Brugada syndrome: incidence and management. ¹ ” According to Santoro et al., fever is a common adverse effect in BS patients following COVID‐19 vaccination, and careful monitoring of body temperature and rapid treatment with an antipyretic medicine may be required. ¹ While the COVID‐19 vaccination is medically successful, we are all worried about unforeseen repercussions. The vaccine recipients in this study experienced negative side effects, albeit a definite diagnosis remains challenging. Fever is frequently reported as a side effect of the COVID‐19 vaccination. However, no inferences can be drawn because there is no pre‐vaccination information on vaccine recipients' health and immunological status. Recognizing that the patient may have a comorbidity that is causing the condition is a fundamental concept. Co‐infections, for example, may occur upon inoculation and be misinterpreted as side effects. ² Some possible coinfections can produce neuromuscular problems, which can be mistaken as a side effect of the COVID‐19 vaccine. Similarly, the effect of concurrent vaccination medicine must be acknowledged. A thorough examination is essential to rule out any other possibilities before making a diagnosis, which should include a virology profile for any other medically significant viral disease that can cause febrile illness after vaccination.