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. 2022 Jul 21;15(17):e202200362. doi: 10.1002/cssc.202200362

Scheme 6.

Scheme 6

Substrate scope.[a] [a] Reaction conditions: 8 (0.20 mmol), 9 (0.34 mmol), 3 (0.30 mmol), silica (200 mg); series A: AcOH (0.5 equiv.); series B: Yb(OTf)3 (0.1 equiv.). [b] Chromatographic separation of the diastereomers. [c] Results of reactions on a 1.0 mmol scale. n.d.=not determined. Adapted with permission from Ref. [58]. Copyright 2021, American Chemical Society.