Figure 3. ApoA-I inhibits human the surface expression P-selectin surface expression but not that of αiibβiii-integrin in washed human platelets.
A. P-selectin surface expression quantified by Mean fluorescence intensity (MFI)±SEM of anti-P-selectin antibody (arbitrary units, AU) on platelets stimulated with convulxin or AA after pre-treatment with NS (black bar) or apoA-I (n=4, charcoal gray bar). ApoA-I pretreatment inhibited the convulxin- or AA-induced increase in P-selectin surface expression (*=p<0.05). B. αiibβiii-integrin (PAC-1) surface expression (MFI) expressed as the mean±SEM on platelets stimulated with convulxin or AA after pre-treatment with normal saline (black) or apoA-I (charcoal gray) apoA-I preincubation did not alter PAC-1 surface expression to either convulxin or AA.