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. 2022 Oct 5;8(10):e10972. doi: 10.1016/j.heliyon.2022.e10972

Table 1.

Weights of body (BW), left kidney, right kidney, and heart of the 2-kidneys-1-clip (2K1C) hypertensive and the sham operation (SO) groups after daily administration of either distilled water (control) or monosodium glutamate (MSG) at the dose of 80, 160, and 320 mg/kg BW/day for 8 weeks.

Body/organ weight SO
2K1C
Control MSG-80 MSG-160 MSG-320 Control MSG-80 MSG-160 MSG-320
BW changes (g) 177 ± 6 196 ± 10 201 ± 11 182 ± 4 188 ± 14 201 ± 11 203 ± 11 200 ± 6
Left kidney (g% BW) 0.30 ± 0.01 0.30 ± 0.01 0.30 ± 0.02 0.29 ± 0.01 0.27 ± 0.01∗ 0.26 ± 0.01∗ 0.25 ± 0.01∗ 0.26 ± 0.01∗
Right kidney (g% BW) 0.29 ± 0.01 0.30 ± 0.01 0.29 ± 0.01 0.28 ± 0.01 0.32 ± 0.01∗ 0.32 ± 0.01∗ 0.32 ± 0.01∗ 0.32 ± 0.01∗
Cardiac mass (g% BW) 0.23 ± 0.01 0.24 ± 0.01 0.24 ± 0.01 0.24 ± 0.01 0.26 ± 0.01∗ 0.27 ± 0.01∗ 0.27 ± 0.01∗ 0.26 ± 0.01∗

BW change = BW after MSG administration − BW before MSG administration.

The weight of each organ was represented as the relative organ weight (g% BW).

Data expressed as mean ± S.E.M. ∗p < 0.05 in comparison to SO control.