Table 4.

Some crucial functions of Lactobacilli strains.

Functional Properties	Example	Reference
Regulating immune system	Jang et al. evaluated immunometabolic functions of L. fermentum strains (KBL374 and KBL375) isolated from the feces of healthy Koreans.	[133]
Regulating the balance of blood glucose, blood lipid, and blood pressure	Li et al. found that L. plantarum X1 can alleviate the symptoms of diabetes by improving the level of short-chain fatty acids in type 2 diabetic mice.	[134]
Antimicrobial activity	Lim et al. found that L. paracasei BK 57 has antagonistic effect on Helicobacter pylori and can be used as potential antibiotics.	[135]
Lower blood pressure	Ong et al. found that L. paracasei can isolate and purify ACE inhibitory peptides from cheddar cheese.	[31]
Antitumor	Rajoka et al. found that the antiproliferative activity of the fermentation supernatant of L. paracasei SR 4 on cervical cancer cells was up to 89%. L. paracasei showed high anti-cancer activity by promoting the up-regulation of BAX, BAD, caspase3, caspase8, and caspase9 genes and down-regulating the expression of the Bcl-2 gene.	[136]
Antioxidant	Suo et al. found that L. paracasei ybJ 01 can significantly improve D-galactose, induced the ability of serum superoxide dismutase (SOD), glutathione peroxidase and total antioxidant in mice, and inhibited the production of malondialdehyde.	[137]