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. 2022 Aug 24;38(20):4771–4781. doi: 10.1093/bioinformatics/btac578

Table 1.

Example snapshot of our HGv1 dataset: glucagon and adiponectin hormones along with their dominant source/target tissue(s) and GO terms

Hormone source target tissue(s) Source terms Target terms
Glucagon pancreas → liver GO: 0070091 (glucagon secretion) GO: 0033762 (response to glucagon)
GO: 0004967 (glucagon receptor activity)
GO: 0120116 (glucagon processing) GO: 0031769 (glucagon receptor binding)
Adiponectin adipose → skeletal muscle, ooctyes, pre-implantation embryos GO: 0070162 (adiponectin secretion) GO: 0055100 (adiponectin binding)
GO: 0033211 (adiponectin-activated signaling pathway)