Figure 4.
JND4135 occupies TRK protein for a long time. (A) Affinity activity of JND 4135 and reported TRKs inhibitors on TRKC and TRKC-G696C protein using BLI assays; (B) Koff values of JND4135 and reported TRKs inhibitors on TRKC and TRKC-G696C.
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