Skip to main content
. 2022 Oct 3;27(19):6554. doi: 10.3390/molecules27196554

Table 4.

Predictions regarding the metabolism of the stereoisomers of triticonazole (TTZ): CYP—cytochrome, s—substrate, i—inhibitor.

Stereoisomer CYP
1A2 s
CYP
1A2 i
CYP
2C19 s
CYP
2C19 i
CYP
2C9 s
CYP
2C9 i
CYP
2D6 s
CYP2
CD6 i
CYP
3A4 s
CYP
3A4 i
(R)-TTZ 0.392 0.975 0.452 0.922 0.281 0.795 0.122 0.516 0.816 0.873
(S)-TTZ 0.481 0.976 0.484 0.894 0.104 0.564 0.066 0.414 0.718 0.790