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. 2022 Sep 2;11:e78823. doi: 10.7554/eLife.78823

Figure 5. Comparison of viscoelastic cell properties measured with shear flow deformability cytometry (SF-DC) and AFM.

Figure 5.

a. Stiffness k versus fluidity α of THP1 cells (n=5000) measured with SF-DC at a pressure of 2 bar, 2% alginate solution. Colors represent Gaussian kernel density. Histograms show the probability density distributions of k (top) and α (side) with Gaussian kernel density estimates (blue line). b, AFM measurements of THP1 cells. Each point represents k and α from one cell, each obtained from the fit of Equation 24 to 3 or more force-indentation curves for each cell. c, Typical force-indentation curve (blue line) and fit with Equation 24 (orange line).