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. 2022 Oct 19;611(7935):312–319. doi: 10.1038/s41586-022-05349-x

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Fig. 4 — a–d, Effect of genotype upon cytokine levels for granulocyte colony-stimulating factor (G-CSF) (a), interleukin-1β (IL-1β) (b), interleukin 10 (IL-10) (c) and C-C motif chemokine ligand 3 (CCL3) (d). Remaining cytokines showed no significant effects and are included in Supplementary Table 7. e, Boxplots showing the percentage of bacteria killed (y axis) by macrophages infected for 24 h as a function of ERAP2 genotype (x axis). The percentage of bacteria killed was calculated as the CFU_2 h − CFU_24 h/CFU_2 h, where CFU is colony-forming unit. The P value results from a linear model examining the association between ERAP2 single nucleotide polymorphism genotypes (SNP) (coded as the number of protective rs2549794 alleles found in each individual: 0, 1 or 2) and the percentage of bacteria killed.