(A) Documented outbreaks of simian arteriviruses in primate facilities. Locations of affected facilities are shown by colored circles on the map and timeline. Several facilities experienced multiple outbreaks. (B) Phylogeny of representative viruses within the order Nidovirales, including all published simian arteriviruses, based on an alignment of concatenated RNA-directed RNA polymerase (RdRp) and helicase genes. Arteriviruses known to have caused outbreaks in primate facilities are written in red. The tree is drawn to scale, with branch lengths measured in the number of substitutions per site and bootstrap values shown for major nodes. Asterisks indicate nodes with 100% support. (C) Geographical ranges of primate species known to be infected with simian arteriviruses. Sampling sites are indicated by black stars. *Only detected in captivity; †Kafue kinda chacma baboon virus (KKCBV) was discovered in kinda x chacma hybrid baboons, within Kafue National Park, as shown as an inset in red (Chiou et al., 2021).