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. 2022 Aug 25;22(11):450. doi: 10.1016/j.bjae.2022.07.002

Corrigendum to ‘Cerebral circulation II: pathophysiology and monitoring’ [BJA Education 22 (2022) 282–8]

Andrea Lavinio 1
PMCID: PMC9596282  PMID: 36304914

The authors regret that an error was present in Table 1. The correct table appears below.

Table 1.

Monitoring modalities. BIS, bispectral index; EVD, external ventricular drains; MCAfv, MCA mean flow velocity; PSI, patient state index; rSO2, cerebral regional oxygen saturation; SR, suppression ratio.

Modality Main indications Overview Advantages Limitations Interpretation
Near infrared spectroscopy (NIRS) Any procedure at risk of POD, POCD and perioperative stroke (older patients, history of cerebrovascular disease or cognitive decline, major surgery). Differential absorption of near-infrared light by oxyhaemoglobin and deoxyhaemoglobin (rSO2). Safe, easy to use, low cost. Provides continuous information on adequacy of cerebral oxygen delivery. Determines oxygenation under the optodes (i.e. regional). Requires further validation. A reduction of rSO2 >20% from baseline or an absolute value below 50% may indicate cerebral hypoperfusion.
Processed electroenecephalography (pEEG) Proprietary algorithmic analysis of EEG (e.g. PSI, BIS). A reduction in indices during steady anaesthetic state correlates with critical reduction in CBF. Safe, easy to use, low cost. Detects patients at risk of oversedation, delayed emergence or intraoperative awareness. Maps frontal cortical activity. Rapidly evolving technology. Requires further validation. A reduction of PSI/BIS >30% indicates cerebral hypoperfusion. SR ≥50% indicates close-to-maximum suppression of CMRO2.
Transcranial Doppler (TCD) Aortic arch and carotid surgery. Patients at risk of intracranial hypertension in whom invasive ICP monitoring is not indicated. Pulsed Doppler probes assess flow velocities in the circle of Willis. Allows continuous assessment of cerebral autoregulation, detection of emboli and non-invasive ICP monitoring. Technically challenging. Normal or high flow velocities do not necessarily indicate adequate perfusion (i.e. vasospasm). No information on oxygen extraction and adequacy of perfusion. A reduction MCAfv >50% from baseline or a value below 25 cm s−1 indicates high risk of postoperative stroke. Reduced or absent diastolic flow indicates ICP close or exceeding diastolic blood pressure.
Intracranial pressure (ICP) Extracranial surgery in patients at risk of intracranial hypertension (i.e. damage-control or orthopaedic surgery after major trauma). Intraparenchymal or intraventricular pressure monitoring allows prompt identification of CBF compromise caused by intracranial hypertension. Well validated in traumatic brain injury. Continuous assessment of CPP. EVDs allow correction of ICP by means of CSF drainage. Invasive. Potentially significant complications (bleeding, infection). Does not assess adequacy of oxygen delivery. ICP >20 mmHg indicates a risk of herniation. CPP <50 mmHg indicates risk of cerebral hypoperfusion.

The author would like to apologise for any inconvenience caused.


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