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. 2022 Oct 10;14(10):2156. doi: 10.3390/pharmaceutics14102156

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) MRI images and median values of the decrease in T₁ and T₂ weighted images in relation to the background signal for blood clots of 48, 24, 4, 1 h, and 0 h of age incubated with KCREKA-NPs, PEG-NPs, or PBS. (B) Number of positive pixels above the background signal for the T₁ and T₂ signals for blood clots of 48, 24, 4, 1 h, and 0 h of age incubated with KCREKA-NPs, PEG-NPs, or PBS. *** p < 0.001 using one way ANOVA followed by Kruskal-Wallis test.