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. 2022 Sep 9;42(7):1925–1939. doi: 10.1148/rg.220073

Figure 15.

Complications of targeted drug therapy in an 85-year-old woman with adenocarcinoma who was treated with osimertinib. (A, B) Axial pretreatment CT images show a mass (arrow in A) in the right middle lobe. The ground-glass abnormality and reticulation (arrowheads) seen in the subpleural area suggest ILA. The patient’s Krebs von den Lungen 6 and surfactant protein D levels were normal. (C, D) Axial CT images at 5 months of treatment show the mass (white arrow in C), and diffuse ground-glass abnormality and consolidation (black arrows), which indicate pneumonitis. The patient was short of breath and was treated with steroids.

Complications of targeted drug therapy in an 85-year-old woman with adenocarcinoma who was treated with osimertinib. (A, B) Axial pretreatment CT images show a mass (arrow in A) in the right middle lobe. The ground-glass abnormality and reticulation (arrowheads) seen in the subpleural area suggest ILA. The patient’s Krebs von den Lungen 6 and surfactant protein D levels were normal. (C, D) Axial CT images at 5 months of treatment show the mass (white arrow in C), and diffuse ground-glass abnormality and consolidation (black arrows), which indicate pneumonitis. The patient was short of breath and was treated with steroids.