The authors have unfortunately discovered that the originally published version of this article contains errors. These errors lead to minor changes of the paper, but need to be corrected.
In this corrigendum, we supply the corrected data in Material and Methods section and Table II.
Table II.
Relationships between demography, clinical and preoperative biochemical wound fluid markers, and the splitthickness skin graft (STSG) healing outcome 12 weeks after transplantation of venous leg ulcers (changes highlighted)
| STSG healing |
p-value | ||
|---|---|---|---|
| Good (n = 10) | Poor (n = 7) | ||
| Female/Male, n | 4/6 | 6/1 | 0.134a |
| Age, years, mean ± SEM | 74 ± 4.5 | 71 ± 4.7 | 0.637b |
| Ulcer duration, months, mean ± SEM | 19 ± 6.8 | 140 ± 120 | 0.335b |
| Ulcer size, cm2, mean ± SEM | 30 ± 6.8 | 30 ± 4.5 | 0.949b |
| Granulation tissue, %, mean ± SEM | 68 ± 11 | 88 ± 8.4 | 0.171b |
| Protein, mg/ml, mean ± SEM | 42 ± 4.6 | 46 ± 2.8 | 0.486b |
| LPS, ng/ml, mean ± SEM | 22 ± 7.7 | 8.2 ± 3.3 | 0.130b |
| TNF-α, ng/ml, mean ± SEM | 2.9 ±1.2 | 3.0 ± 0.98 | 0.906b |
| HNE activity, pmol/ml, mean ± SEM | 310 ± 140 | 140 ± 34 | 0.262b |
| MPO activity, U/ml, mean ± SEM | 61 ± 21 | 34 ± 4.3 | 0.238b |
| MMP activity, pmol/ml, mean ± SEM | 3,300 ± 1,600 | 5,000 ± 1,800 | 0.486b |
| MMP-2, μg/ml, mean ± SEM | 0.64 ± 0.35 | 0.57 ± 0.33 | 0.896b |
| MMP-9, μg/ml, mean ± SEM | 147 ± 27 | 58 ± 15 | 0.0116b |
| MMP-8, μg/ml, mean ± SEM | 14 ± 3.8 | 7.7 ± 1.7 | 0.132b |
| TIMP-1, μg/ml, mean ± SEM | 1.0 ± 0.17 | 0.86 ± 0.24 | 0.585b |
| Woundchek, nc | 6/9d | 4/6d | 1.00a |
| Cellular bioactivity, %, mean ± SEM | |||
| HaCaT | 67 ± 6.3 | 46 ± 7.0 | 0.0443b |
| HDVEC | 45 ± 10 | 23 ± 4.4 | 0.0664b |
| HDF | 75 ± 12 | 49 ± 9.9 | 0.109b |
Fisher’s exact test.
Two-tailed t-test with Welch’s correction.
No wound fluid remained from patient number 10 to perform this analysis.
Number of tests with elevated levels of inflammatory proteinase activity/total number of tests (=wound fluid samples).
SEM: standard error of mean; LPS: lipopolysaccharide; TNF: tumour necrosis factor; HNE: human neutrophil elastase; MPO: myeloperoxidase; MMP: matrix metalloproteinase; TIMP: tissue inhibitor of metalloproteinases; HaCaT: human keratinocytes; HDVEC: human dermal microvascular endothelial cells; HDF: human dermal fibroblasts.
These corrections do not alter the study’s findings of significance or overall interpretation of the study results. The authors regret for any inconvenience caused.
MATERIALS AND METHODS
In the Material and Methods the following sentence is changed:
Original sentence
TIMP-1 (ab18793) was determined by a kit from Abcam (Cambridge, UK), and LPS (MBS702450) was determined by a kit from MyBioSource (San Diego, CA, USA).
Corrected sentence
TIMP-1 (ab187394) was determined by a kit from Abcam (Cambridge, UK), and LPS (MBS702450) was determined by a kit from MyBioSource (San Diego, CA, USA).