Table 4. Studies associated with cffDNA analysis of aneuploidies.

SPR: Slide positivity rate, PPV: Positive predictive value, SCA: Sex chromosomal abnormalities

Article/ study	Sample size	Result
Lai et al. [24]	86,193 pregnant females with reportable results	SPR: 0.6%, PPV (SCA): 38%, i.e., n=505 Sensitivity:  45, X: 88.46%; 47, XXY: 100%; 47, XXX: 100%; 47, XYY: 100%
Lu et al. [25]	222,107 pregnant females with reportable results	PPV: 45, X: 18.14%; 47, XXY: 80.29%; 47, XXX: 58.73%; 47, XYY: 71.19%
Margiotti et al. [26]	9,985 pregnant females with reportable results	SCA Incidence: 0.31%, i.e., 31 positive cases of which 77.3% were true positive, i.e., 17 true positive cases out of which 45, X: 53%; 47, XXY: 23.5 %; 47, XXX: 17.6%; 47, XXY: 5.9%