Table 3.

ADME profiles for all synthesised compounds (15a–r).

S. No.	Comp	M.Wt	H-Bond Accept	H-Bond Donor	LogP o/w	Absorption	Rule of 5
1	15a	449.57	2	2	3.12	100	0
2	15b	435.54	2	2	2.82	100	0
3	15c	514.44	2	2	3.38	100	1
4	15d	401.53	2	2	2.8	100	0
5	15e	449.57	2	2	3.22	100	0
6	15f	525.62	5	2	3.91	100	1
7	15g	469.99	2	2	3.06	100	0
8	15h	441.59	2	2	2.85	100	0
9	15i	465.57	3	2	3	100	0
10	15j	453.53	3	2	2.98	100	0
11	15k	465.57	3	2	3.22	100	0
12	15l	465.57	3	2	2.75	100	0
13	15m	415.55	2	2	3.13	100	0
14	15o	387.5	2	2	2.66	100	0
15	15n	401.53	2	2	2.82	100	0
16	15p	469.99	2	2	3.06	100	0
17	15q	399.51	2	2	2.79	100	0
18	15r	399.51	2	2	3.01	100	0