Table 2.
Effect of ROS scavengers on curcumin activity in prostate cancer cell lines.
| Cancer Cell Line | Dose | Apoptosis (Folds) | Effect of Scavengers |
|---|---|---|---|
| PC3 | Untreated | - | - |
| Curcumin (25 µM) | 2.54 | - | |
| Thiourea | 1.58 | 37.79 | |
| Catalase | 2.03 | 20.07 | |
| SOD | 1.77 | 30.31 | |
| LNCaP | Untreated | - | - |
| Curcumin (25 µM) | 3.67 | - | |
| Thiourea | 1.84 | 49.86 | |
| Catalase | 2.01 | 45.23 | |
| SOD | 1.94 | 47.13 | |
| DU145 | Untreated | - | - |
| Curcumin (25 µM) | 3.46 | - | |
| Thiourea | 1.78 | 48.55 | |
| Catalase | 2.13 | 38.43 | |
| SOD | 1.97 | 43.06 | |
| C42B | Untreated | - | - |
| Curcumin (25 µM) | 3.10 | - | |
| Thiourea | 2.17 | 30.00 | |
| Catalase | 2.69 | 13.22 | |
| SOD | 2.51 | 19.03 |