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. 2022 Nov 16;14(1):2145929. doi: 10.1080/19420862.2022.2145929

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© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Three different mAb glycovariants were injected into minipigs and serum sampled at different consecutive time points. Individual PK curves were created combining mAb glycosylation profiles and absolute concentrations measured by LC-MS and ELISA, respectively. — Overview of animal experiments and analytical workflow.