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. 2022 Aug 17;101(10):959–969. doi: 10.1159/000525604

Table 1.

Overview of identified studies

First author Year Study period Country Pts., n Endpoint
Quality assesment
PMV weaning failure study type sample* follow-up** adjustment***
Béduneau et al. [1] 2016 Apr 13 to Jun 13 France, Spain, 2,729 Yes* Multicentric, prospective Yes Unclear Yes
Switzerland
Chang et al. [19] 2018 Aug 13 to Oct 15 Taiwan 251 Yes Monocentric, retrospective No Yes Yes
Clark et al. [18] 2013 Jan 9 to Jun 10 USA 130 Yes Monocentric, retrospective Yes No Yes
Clark et al. [20] 2018 Unknown USA 173 Yes Monocentric, prospective Unclear No Yes
Figueroa-Casas et al. [24]
2015 Mar 12–14 USA 282 Yes Monocentic, prospective Yes No Yes
Ghiani et al. [31] 2020 Jan 14 to Oct 18 Germany 263 Yes Monocentic, retrospective No Yes Yes
Goligher et al. [25] 2017 May 13 to Jan 16 Canada 191 Yes Monocentic, prospective Yes No Yes
Greenberg et al. [23] 2018 2011–2015 USA 372 Yes Monocentic, retrospective Unclear No Yes
Hermans et al. [22] 2007 Mar 2 to May 05 Belgium 420 Yes Monocentic, prospective sub No No Yes
Analysis of an RCT [33]
Hsieh et al. [29] 2019 Dec 9 to Dec 11 Taiwan 3,602 Yes* Monocentic, prospective Unclear Yes Yes
Huang et al. [32] 2019 Jan 12 to Dec. 17 Taiwan 574 Yes Monocentic, retrospective No Yes Yes
Li et al. [9] 2016 Jul 7 to Jul 11 China 302 Yes Multicentric prospective No Yes No
1-d prevalence study
Magnet et al. [6] 2018 Jan 9 and Dec 11 Germany 124 Yes Monocentic, retrospective No Yes Yes
Muzaffa et al. [35] 2016 May 14 to Apr 15 India 49 Yes Monocentic, prospective No Yes Yes
Pan et al. [17] 2011 Dec 8 to Nov 9 Taiwan 154 Yes Monocentic, retrospective Yes Yes Yes
Papuzinski et al. [16] 2013 Jun 2011 to Jun 2012 Chile 103 Yes Monocentic, retrospective Yes No Yes
Pu et al. [27] 2015 Jan 12 to Dec 12 China 343 Yes* Multicentric prospective Unclear Yes Yes
Saiphoklang et al. [36] 2018 Jun 12 to Dec 12 Thailand 103 Yes Monocentic, prospective Unclear Yes Yes
Sellares et al. [28] 2010 5-year period Spain 181 Yes* Monocentic, prospective Unclear Yes Yes
Tseng et al. [37] 2016 Jan 11 to Dec 11 Taiwan 285 Yes Monocentic, prospective No Yes Yes
Wang et al. [21] 2018 Jan 15 − Dec 17 China 56 Yes Monocentic, retrospective No No Yes
Windisch et al. [7] 2020 2011 and 2015 Germany 11,424 Yes Multicentric retrospective No Yes Yes
Wu et al. [38] 2009 Nov 99 to Dec 5 Taiwan 1,307 Yes Monocentic, retrospective No Yes Yes

The risk of bias was systematically assessed using an adapted version of the Knowledge Translation Program's prediction worksheet criteria. In accordance with these requirements, three categories were considered.

*

Was a well-defined, representative sample of patients assembled at a common and early point in the course of their disease?

**

Was patient follow-up sufficiently long?

***

Given the large number of factors identified in the various studies, the fact that a multivariate or stratified analysis was performed was already considered positive.