Appendix 3—figure 27. The increase in the 2^nd and 3^rd central moments of the phenotypic distribution.

(A and C) The increase is largely driven by alleles with large effects. Specifically, there are substantial increases only in the non-Lande cases, that is, those with an abundance of new mutations with $a^2>4$ . (B and D) We conjecture that the compound parameters that largely determine the increase in moments are: ${(\mathrm{\Lambda }/\sqrt{V_A(0)})}^2$ for the 2^nd central moment (B) and $\mathrm{\Lambda }/\delta$ for the 3^rd. Note that the slight differences among curves in the non-Lande case are short-lived (time is measured on a log-scale). The simulation results were generated using the all allele simulation, as described in Section 2.1.