Table 2.

Area under the curve (AUC) calculated from non-decay corrected biodistribution data of [²²⁵Ac]Ac-mcp-M-alb-PSMA and [²²⁵Ac]Ac-mcp-D-alb-PSMA and the ratios of AUCs.

Radio-conjugate	AUC [%ID/g.h]
	Tumor	Blood	Kidneys	Liver
[225Ac]Ac-mcp-M-alb-PSMA	3494 ± 194	132 ± 7.2	2269 ± 288	119 ± 4.6
[225Ac]Ac-mcp-D-alb-PSMA	6455 ± 411	249 ± 10.4	4519 ± 193	328 ± 15.8
	AUCTu-to-AUCBl	AUCTu-to-AUCKi	AUCTu-to-AUCLi
[225Ac]Ac-mcp-M-alb-PSMA	26	1.5	29
[225Ac]Ac-mcp-D-alb-PSMA	26	1.4	20

The data of AUCs are presented as mean values ± SD with n=4 for [²²⁵Ac]Ac-mcp-M-alb-PSMA and n=3 for [²²⁵Ac]Ac-mcp-D-alb-PSMA.