Table 3.
Effects of TCI227 on serum biochemical parameters in PO-induced hyperuricemia SD rats.
| Groups | Control | HC | HC + LD | HC + MD | HC + HD | HC + AP |
|---|---|---|---|---|---|---|
| Glucose (mg/dL) | 97.25 ± 9.95 | 97.75 ± 12.96 | 89.13 ± 5.74 | 97.38 ± 19.04 | 90.13 ± 8.59 | 91.13 ± 10.88 |
| Total cholesterol (mg/dL) | 44.88 ± 5.87 | 46.00 ± 9.59 | 44.75 ± 11.46 | 48.88 ± 7.62 | 48.38 ± 8.45 | 40.63 ± 8.23 |
| Triglyceride (mg/dL) | 83.75 ± 29.50 | 50.88 ± 12.18 # | 45.00 ± 13.66 | 43.75 ± 14.32 | 42.38 ± 10.68 | 37.50 ± 5.86 * |
| AST (U/L) | 75.50 ± 5.63 | 77.25 ± 14.83 | 93.88 ± 36.76 | 69.63 ± 13.54 | 77.75 ± 14.44 | 73.63 ± 11.21 |
| ALT (U/L) | 38.88 ± 6.85 | 30.13 ± 9.39 | 36.50 ± 6.30 | 31.50 ± 8.80 | 37.50 ± 15.86 | 30.50 ± 8.77 |
| BUN (mg/dL) | 14.38 ± 1.30 | 14.13 ± 1.89 | 14.38 ± 2.88 | 13.25 ± 1.83 | 14.75 ± 2.92 | 16.50 ± 4.44 |
| Creatinine (mg/dL) | 0.35 ± 0.05 | 0.34 ± 0.04 | 0.32 ± 0.06 | 0.28 ± 0.03 ** | 0.31 ± 0.03 | 0.34 ± 0.05 |
| Na+ (mmol/L) | 145.25 ± 1.67 | 141.75 ± 1.75 ## | 142.38 ± 1.06 | 141.25 ± 1.58 | 141.38 ± 2.20 | 144.00 ± 1.85 |
| K+ (mmol/L) | 6.36 ± 0.17 | 6.64 ± 0.67 | 6.84 ± 0.71 | 6.84 ± 0.45 | 6.74 ± 1.01 | 6.48 ± 0.50 |
| Cl− (mmol/L) | 96.76 ± 1.38 | 99.05 ± 2.71 # | 99.45 ± 2.41 | 98.49 ± 1.39 | 98.70 ± 1.93 | 100.15 ± 0.98 |
The reported values are means ± SD (n = 8); # significantly differs from the HC group (p < 0.05); ## significantly differs from the HC group (p < 0.01); * significantly differs from the HC group (p < 0.05); ** significantly differs from the HC group (p < 0.01).