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. 2022 Nov 8;14(11):2413. doi: 10.3390/pharmaceutics14112413

Figure 9.

Figure 9

Effects of OEO-PbH on the viability of human DCs. DCs were cultured for 7 days with GM-CSF and IL-4. Cells were subsequently stimulated without LPS or with LPS and treated with the OEO-PbH at different concentrations for 24 h. Viability (A) as well as the absolute number of DCs (B) were assessed using flow cytometry. Staurosporine-treated DCs served as a positive control (black bar). (A) Frequency of DAPI+ (dead cells). (B) Absolute cell number in cell culture 24 h after stimulation calculated as cells/mL. Data expressed as mean ± SEM (n = 6 donors); # indicates comparisons to the respective blank control (B-PbH-treated DCs) using RM one-way ANOVA; * indicates group comparisons between LPS-treated and LPS-untreated cells using paired t-test (# p < 0.05; ### p < 0.001; ns = not significant).