Table 2.
Participant characteristics by COVID-19 vaccination status among people with HIV tested for SARS-CoV-2 infection between December 14, 2020 and November 21, 2021, Ontario, Canada.
| Unvaccinated | Received one dose ≥14 days before index date | Received two doses ≥7 days before index date | ||||||
| N | % | N | % | SD | N | % | SD | |
| Total | 5275 | 100.0 | 1118 | 100.0 | 2759 | 100.0 | ||
| Lab-confirmed SARS-CoV-2 infection | ||||||||
| Test-positive case | 640 | 12.1 | 63 | 5.6 | 0.23 | 53 | 1.9 | 0.41 |
| Test-negative control | 4635 | 87.9 | 1055 | 94.4 | 0.23 | 2706 | 98.1 | 0.41 |
| Age group (years) | ||||||||
| 19–29 | 449 | 8.5 | 64 | 5.7 | 0.11 | 177 | 6.4 | 0.08 |
| 30–39 | 1085 | 20.6 | 174 | 15.6 | 0.13 | 537 | 19.5 | 0.03 |
| 40–49 | 1259 | 23.9 | 242 | 21.6 | 0.05 | 620 | 22.5 | 0.03 |
| 50–59 | 1540 | 29.2 | 340 | 30.4 | 0.03 | 813 | 29.5 | 0.01 |
| ≥60 | 942 | 17.9 | 298 | 26.7 | 0.21 | 612 | 22.2 | 0.11 |
| Sex | ||||||||
| Male | 3898 | 73.9 | 834 | 74.6 | 0.02 | 2114 | 76.6 | 0.06 |
| Female | 1377 | 26.1 | 284 | 25.4 | 0.02 | 645 | 23.4 | 0.06 |
| Year-month of specimen collection | ||||||||
| 2020-12 | 683 | 12.9 | 0 | 0.0 | 0.55 | 0 | 0.0 | 0.55 |
| 2021-01 | 1099 | 20.8 | 14 | 1.3 | 0.66 | ≤5 | ≤0.2 | - |
| 2021-02 | 871 | 16.5 | 23 | 2.1 | 0.51 | 40-44 | 1.4–1.6 | - |
| 2021-03 | 1000 | 19.0 | 52 | 4.7 | 0.45 | 80 | 2.9 | 0.53 |
| 2021-04 | 739 | 14.0 | 223 | 19.9 | 0.16 | 80 | 2.9 | 0.41 |
| 2021-05 | 370 | 7.0 | 346 | 30.9 | 0.64 | 72 | 2.6 | 0.21 |
| 2021-06 | 117 | 2.2 | 269 | 24.1 | 0.68 | 138 | 5.0 | 0.15 |
| 2021-07 | 108 | 2.0 | 80 | 7.2 | 0.25 | 363 | 13.2 | 0.43 |
| 2021-08 | 94 | 1.8 | 50 | 4.5 | 0.16 | 503 | 18.2 | 0.57 |
| 2021-09 | 84 | 1.6 | 25 | 2.2 | 0.05 | 543 | 19.7 | 0.61 |
| 2021-10 | 69 | 1.3 | 26 | 2.3 | 0.08 | 571 | 20.7 | 0.65 |
| 2021-11 | 41 | 0.8 | 10 | 0.9 | 0.01 | 363 | 13.2 | 0.50 |
| Pandemic wave | ||||||||
| Wave 2: December 14, 2020 to March 6, 2021 | 2893 | 54.8 | 39 | 3.5 | 1.37 | 63 | 2.3 | 1.43 |
| Wave 3: March 7, 2021 to June 26, 2021 | 1979 | 37.5 | 861 | 77.0 | 0.87 | 319 | 11.6 | 0.63 |
| Wave 4: June 27, 2021 to November 21, 2021 | 403 | 7.6 | 218 | 19.5 | 0.35 | 2377 | 86.2 | 2.55 |
| Public Health Region | ||||||||
| Toronto | 2645 | 50.1 | 551 | 49.3 | 0.02 | 1431 | 51.9 | 0.03 |
| Central East | 149 | 2.8 | 42 | 3.8 | 0.05 | 94 | 3.4 | 0.03 |
| Central West | 699 | 13.3 | 168 | 15.0 | 0.05 | 356 | 12.9 | 0.01 |
| Durham | 133 | 2.5 | 33 | 3.0 | 0.03 | 72 | 2.6 | 0.01 |
| Eastern | 169 | 3.2 | 44 | 3.9 | 0.04 | 70 | 2.5 | 0.04 |
| Northern | 212 | 4.0 | 43 | 3.8 | 0.01 | 95 | 3.4 | 0.03 |
| Ottawa | 390 | 7.4 | 73 | 6.5 | 0.03 | 207 | 7.5 | 0.00 |
| Peel | 292 | 5.5 | 58 | 5.2 | 0.02 | 145 | 5.3 | 0.01 |
| South West | 427 | 8.1 | 79 | 7.1 | 0.04 | 207 | 7.5 | 0.02 |
| York | 159 | 3.0 | 27 | 2.4 | 0.04 | 82 | 3.0 | 0.00 |
| Number of tests in 3 months before December 14, 2020 | ||||||||
| 0 | 3682 | 69.8 | 762 | 68.2 | 0.04 | 1820 | 66.0 | 0.08 |
| 1 | 1001 | 19.0 | 204 | 18.2 | 0.02 | 516 | 18.7 | 0.01 |
| 2+ | 592 | 11.2 | 152 | 13.6 | 0.07 | 423 | 15.3 | 0.12 |
| Receipt of 2019/20 or 2020/21 flu vaccine | ||||||||
| Neither season | 2966 | 56.2 | 565 | 50.5 | 0.11 | 1313 | 47.6 | 0.17 |
| Either season | 1307 | 24.8 | 272 | 24.3 | 0.01 | 771 | 27.9 | 0.07 |
| Both seasons | 1002 | 19.0 | 281 | 25.1 | 0.15 | 675 | 24.5 | 0.13 |
| Number of comorbidities | ||||||||
| 0 | 2526 | 48.6 | 481 | 43.0 | 0.11 | 1334 | 48.4 | 0.00 |
| 1 | 1534 | 29.1 | 324 | 29.0 | 0.00 | 783 | 28.4 | 0.02 |
| 2+ | 1179 | 22.4 | 313 | 28.0 | 0.13 | 642 | 23.3 | 0.02 |
| Comorbidities | ||||||||
| Chronic respiratory disease | 1359 | 25.8 | 312 | 27.9 | 0.05 | 684 | 24.8 | 0.02 |
| Hypertension | 1135 | 21.5 | 294 | 26.3 | 0.11 | 688 | 24.9 | 0.08 |
| Diabetes | 654 | 12.4 | 182 | 16.3 | 0.11 | 367 | 13.3 | 0.03 |
| Frailty/dementia | 530 | 10.0 | 133 | 11.9 | 0.06 | 196 | 7.1 | 0.11 |
| Chronic heart disease | 427 | 8.1 | 120 | 10.7 | 0.09 | 228 | 8.3 | 0.01 |
| Chronic kidney disease/dialysis | 329 | 6.2 | 99 | 8.9 | 0.10 | 205 | 7.4 | 0.05 |
| Advanced liver disease | 223 | 4.2 | 65 | 5.8 | 0.07 | 96 | 3.5 | 0.04 |
| Autoimmune disorders | 232 | 4.4 | 54 | 4.8 | 0.02 | 147 | 5.3 | 0.04 |
| History of stroke/TIA | 87 | 1.6 | 31 | 2.8 | 0.08 | 52 | 1.9 | 0.02 |
| Neighborhood-level essential workers quintile | ||||||||
| 1 (0–32.5%) | 1594 | 30.2 | 358 | 32.0 | 0.04 | 997 | 36.1 | 0.13 |
| 2 (32.5–42.3%) | 933 | 17.7 | 196 | 17.5 | 0.00 | 482 | 17.5 | 0.01 |
| 3 (42.3–49.8%) | 888 | 16.8 | 187 | 16.7 | 0.00 | 421 | 15.3 | 0.04 |
| 4 (50.0–57.5%) | 907 | 17.2 | 208 | 18.6 | 0.04 | 431 | 15.6 | 0.04 |
| 5 (57.5–100%) | 953 | 18.1 | 169 | 15.1 | 0.08 | 428 | 15.5 | 0.07 |
| Neighborhood-level average number of persons per dwelling quintile | ||||||||
| 1 (0–2.1) | 2335 | 44.3 | 513 | 45.9 | 0.03 | 1273 | 46.1 | 0.04 |
| 2 (2.2–2.4) | 905 | 17.2 | 192 | 17.2 | 0.00 | 434 | 15.7 | 0.04 |
| 3 (2.5–2.6) | 508 | 9.6 | 101 | 9.0 | 0.02 | 293 | 10.6 | 0.03 |
| 4 (2.7–3.0) | 855 | 16.2 | 187 | 16.7 | 0.01 | 418 | 15.2 | 0.03 |
| 5 (3.1–5.7) | 672 | 12.7 | 125 | 11.2 | 0.05 | 341 | 12.4 | 0.01 |
| Neighborhood-level proportion of persons self-identifying as visible minority quintile | ||||||||
| 1 (0.0–2.2%) | 372 | 7.1 | 91 | 8.1 | 0.04 | 210 | 7.6 | 0.02 |
| 2 (2.2–7.5%) | 490 | 9.3 | 109 | 9.7 | 0.02 | 247 | 9.0 | 0.01 |
| 3 (7.5–18.7%) | 902 | 17.1 | 198 | 17.7 | 0.02 | 468 | 17.0 | 0.00 |
| 4 (18.7–43.5%) | 1660 | 31.5 | 376 | 33.6 | 0.05 | 935 | 33.9 | 0.05 |
| 5 (43.5–100%) | 1851 | 35.1 | 344 | 30.8 | 0.09 | 899 | 32.6 | 0.05 |
| Neighborhood-level median income quintile | ||||||||
| 1 (lowest) | 1989 | 37.7 | 405 | 36.2 | 0.03 | 934 | 33.9 | 0.08 |
| 2 | 1152 | 21.8 | 219 | 19.6 | 0.06 | 570 | 20.7 | 0.03 |
| 3 | 881 | 16.7 | 208 | 18.6 | 0.05 | 526 | 19.1 | 0.06 |
| 4 | 619 | 11.7 | 132 | 11.8 | 0.00 | 360 | 13.0 | 0.04 |
| 5 (highest) | 634 | 12.0 | 154 | 13.8 | 0.05 | 369 | 13.4 | 0.04 |
COVID-19, coronavirus disease 2019; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; SD, standardized difference..