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. 2022 Nov 2;12(11):1054. doi: 10.3390/metabo12111054

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Differential gene expression of the KP enzymes among brain tumors. Low grade gliomas (LGG) and glioblastoma (GBM) were separated according to their IDH wildtype (IDHw) or IDH mutant (IDHm) status, then expression levels of the KP enzymes IDO1 (A), IDO2 (B), TDO2 (C), AFMID (D), AADATnaïve (E), GOT2 (F), KMO (G), KYNU (H), HAAO (I), ACMSD (J), and QPRT (K) were compared with non-tumor brain cortex samples (Ctx), pheochromocytomas and paragangliomas (P & P), and neuroblastomas (NB). * p < 0.05 when considering the Dunn’s test for multiple pairwise comparisons against Ctx.