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. 2022 Nov 29;99(22):e2454–e2463. doi: 10.1212/WNL.0000000000201205

Figure 3. Random-Effects Meta-analysis of Mean WMH Volume Change as %ICV Over Median of 3 Years, Range 1.9–6.7 Years.

Figure 3

Squares represent means and bars the 95% CI. DM2 = diabetes mellitus type 2; healthy/CD = healthy/community-dwelling; MRAW = raw means; VRF = vascular risk factorWMH = white matter hyperintensity.