In the published article, there was an error in Figure 1D as published. To reveal the expression of VEGF-D at week 4 in the allograft group, it had been accidentally replaced by the acquired image of the allograft group at week 8 when we used AI software to typeset for manuscript preparation. The corrected Figure 1 and its caption are shown as below:
Figure 1.
Chronic rejection is associated with lymphangiogenesis in renal allograft. (A) Representative immunofluorescence images of LYVE-1, CD31, and DAPI within sham (n=6 mice), isograft (n=6 mice) and allograft (n=6 mice) kidneys at 1, 4 and 8 weeks respectively. (B, C) Numbers and area counting of LYVE-1+ vessels in high-power field (HPF) at 1, 4 and 8 weeks respectively. (D) Immunohistochemistry of VEGF-C, VEGF-D and FGF-2 expression within sham, isograft and allograft kidneys at 1, 4 and 8 weeks respectively. (E) Positive ratio of VEGF-C, VEGF-D and FGF-2 within sham, isograft and allograft kidneys at 1, 4 and 8 weeks respectively. (F) Relative mRNA expression of VEGF-C, VEGF-D and FGF-2 by qRT-PCR within isograft and allograft kidneys at 1, 4 and 8 weeks respectively, using sham as a reference. (G) Live single CD45- PDPN+ CD31+ LECs isolating from renal allograft by gating technology via flow cytometry, and the population of Ki67+ cells. (H) The ratio of Ki67+ cells in PDPN+CD31+ LECs within sham, isograft and allograft kidneys at 1, 4 and 8 weeks respectively. *P < 0.05, **P < 0.01, ***P < 0.001. Values are mean ± SEM.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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