Table 2.
Pair-wise statistical comparison of identified functional connections and BBB permeability for ROO and EVOO groups. Bold values indicate significantly different.
| Functional Connection | Pair-Wise p-Values | ||||
|---|---|---|---|---|---|
| EVOO2 > EVOO1 | ROO2 vs. ROO1 | EVOO1 vs. ROO2 | EVOO1 vs. ROO1 | EVOO2 > ROO2 | |
| L Precuneus ↔ L Parahippocampal Gyrus | 0.02 | 0.46 | 0.83 | 0.66 | 0.01 |
| R Precuneus ↔ L Parahippocampal Gyrus | 0.02 | 0.41 | 0.78 | 0.50 | 0.05 |
| L Postcentral Gyrus ↔ R Parahippocampal Gyrus | 0.03 | 0.93 | 0.80 | 0.77 | 0.04 |
| L Postcentral Gyrus ↔ L Parahippocampal Gyrus | 0.05 | 0.76 | 0.98 | 0.80 | 0.04 |
| R Postcentral Gyrus ↔ L Parahippocampal Gyrus | 0.05 | 0.31 | 0.50 | 0.91 | 0.01 |
| L Lingual Gyrus ↔ L Parahippocampal Gyrus | 0.04 | 0.22 | 0.84 | 0.34 | 0.05 |
| L Middle Frontal Gyrus ↔ L Parahippocampal Gyrus | 0.05 | 0.65 | 0.36 | 0.52 | 0.01 |
| L Superior Parietal Lobule ↔ L Parahippocampal Gyrus | 0.04 | 0.06 | 0.52 | 0.35 | 0.01 |
| BBB permeability | |||||
| L Parahippocampal Gyrus | 0.00 | 0.60 | 0.69 | 0.27 | 0.00 |
| R Parahippocampal Gyrus | 0.01 | 0.85 | 0.34 | 0.40 | 0.04 |
| L Hippocampus | 0.03 | 0.87 | 0.15 | 0.21 | 0.05 |
| R Hippocampus | 0.04 | 0.99 | 0.70 | 0.71 | 0.03 |
The baseline is presented as (1) and the 6-month is presented as (2). For example, EVOO1 corresponds to the EVOO group at baseline (session 1) and EVOO2 is after 6 months (session 2). Significant p-values (p ≤ 0.05 FDR corrected) are shown in boldface.