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. 2022 Nov 23;14(23):4983. doi: 10.3390/nu14234983

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Treatment with an antibiotics regimen completely reversed aggravated parameters of food allergy. (A) Experimental flow chart. (B) Time course of hypothermia. Rectal temperature was evaluated just after the final oral challenge with OVA (n = 7, Water; n = 6, CMC; n = 6, P80). (C) Diarrhea scores. The extent of diarrhea was examined just after the final oral challenge with OVA (n = 7, Water; n = 6, CMC; n = 6, P80). (D) PAS staining for colonic tissue in food allergy-induced mice treated with an antibiotic regimen plus, water, CMC, or P80. (E) Goblet Cell Score of PAS-stained colonic tissue as of D. (n = 12 per group). One-way ANOVA and Tukey’s Multiple Comparison Test were used to determine significance. Data are the means ± SEM. * p < 0.05; ns, not significant.

Treatment with an antibiotics regimen completely reversed aggravated parameters of food allergy. (A) Experimental flow chart. (B) Time course of hypothermia. Rectal temperature was evaluated just after the final oral challenge with OVA (n = 7, Water; n = 6, CMC; n = 6, P80). (C) Diarrhea scores. The extent of diarrhea was examined just after the final oral challenge with OVA (n = 7, Water; n = 6, CMC; n = 6, P80). (D) PAS staining for colonic tissue in food allergy-induced mice treated with an antibiotic regimen plus, water, CMC, or P80. (E) Goblet Cell Score of PAS-stained colonic tissue as of D. (n = 12 per group). One-way ANOVA and Tukey’s Multiple Comparison Test were used to determine significance. Data are the means ± SEM. * p < 0.05; ns, not significant.