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. Author manuscript; available in PMC: 2024 Apr 1.
Published in final edited form as: Hepatology. 2022 Jul 7;77(4):1164–1180. doi: 10.1002/hep.32608

Figure 2. BA synthesis regulation by alcohol and LDNPs.

Figure 2.

(A) Liver BA levels, serum BA levels, serum C4 levels and hepatic Cyp7a1 mRNA levels. (B) Hepatic protein expression of Cyp7a1. (C) Hepatic mRNA expression of Fxr and Shp. (D) Nuclear (nShp) and cytoplasmic (cShp) protein expression of liver Shp. (E) Serum Fgf15 levels and ileum mRNA expression of Fgf15. (F) Ileum mRNA and protein expression of Fxr. n = 3–5/group.