In the detailed article (1), we missed a reference in the methotrexate (MTX) section about the risk of incorrect administration, by the patients themselves as well as by medical professionals, of MTX over several days rather than once-weekly. It is not uncommon for these multi-day MTX overdoses to end fatally (2). This problem has also been pointed out several times by the Poisons Information Center in Erfurt (3). Unfortunately, past warnings (4) have not resulted in a decrease in these incidents. The Erfurt poison emergency hotline observed cases have nearly doubled, from 13 in 2012 to 22 cases in 2021 (with a total of 175 cases from 2012 to 2021, including 10 deaths). We would therefore like to appeal once again to the medical professionals to take special care in the use of MTX and to remind them of their obligation to provide patients with accurate information.
References
Footnotes
Conflict of interest statement
The authors declare that no conflict of interest exists.
References
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