Corrigendum: Yu et al. PPy@Fe₃O₄ nanoparticles inhibit the proliferation and metastasis of CRC via suppressing the NF-κB signaling pathway and promoting ferroptosis

In the published article, there was an error in the legend for Figure 6 as published. “DLD1” in Figure 6B Legend was incorrectly written as “MGC-803”. The corrected legend appears below.

FIGURE 6.

Anti-tumour activity of PPy@ Fe₃O₄ NPs in nude mouse tumour cell xenografts. (A) Images of subcutaneous xenograft tumors of DLD1 cells. (B) The final tumor weight of DLD1 cells was shown. (C) The tumor volume and change of different groups. (D) The temperature change and (E) infrared thermal imaging of the mice injected with PBS, NPs under laser irradiation. (F) Ki67 staining of the tumors in the control group and other treated groups. (scale bar: 100 μm). (G) H&E staining of the main organs from the control and treatment groups. (scale bar: 250 μm). **p < 0.01.

In the published article, there was an error in Figure 5C and Figure 6B as published. “Invasion” was incorrectly written as “Invation”. The real image in the lower right corner of Figure 5C was incorrect due to a copy error when assembling the images. “NIR” in Figure 6B was incorrectly written as “H₂O₂”. “Control” in Figure 6F was incorrectly written as “Contol”. The corrected Figure 5 and Figure 6 and its caption appear below.

FIGURE 5.

PPy@ Fe₃O₄ NPs suppress CRC cells metastasis by promoting cell ferroptosis and inhibiting NF-κB signaling pathway. (A) Western blot. Colorectal cancer cell line DLD1 was treated with various groups (Control, H₂O₂, NPs and NPs +H₂O₂), and then subjected to Western blot analysis of the key proteins of the NF-κB signaling pathway (Ikk-β, p-Ikk-β, Ikk-α, p-Ikk-α, NF-κB, p-NF-κB, iκB-α, and p-iκB-α). (B) Effects of the ferroptosis inhibitor Ferrostatin-1 on PPy@Fe₃O₄ NPs-induced metastasis-related proteins expression. (C) Transwell showed that PPy@Fe₃O₄ NPs induced cell migration and invasion were abolished after addition of the ferroptosis inhibitor Ferrostatin-1 in CRC cells.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

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