TABLE 1.
Features of the Participants
| Feature | At-Risk for PARDS, N = 35 | Nonsevere PARDS, N = 34 | Severe PARDS, N = 13 |
|---|---|---|---|
| Age, mo | 10 (3–28) | 11 (3–21) | 23 (4–28) |
| Male | 20 (57.1) | 20 (58.8) | 8 (61.5) |
| Ethnicity | |||
| Hispanic/Latino | 2 (5.7) | 0 | 1 (7.7) |
| Not Hispanic/Latino | 32 (91.4) | 34 (100) | 12 (92.3) |
| Unknown/not reported | 1 (2.9) | 0 | 0 |
| Race | |||
| White or White-Hispanic | 13 (37.1) | 10 (29.4) | 4 (30.8) |
| Black or Black-Hispanic | 20 (57.1) | 22 (64.7) | 6 (46.2) |
| Multiple races | 0 | 2 (5.9) | 3 (23.1) |
| Other | 1 (2.9) | 0 | 0 |
| Unknown/not reported | 1 (2.9) | 0 | 0 |
| Pediatric Risk of Mortality-III score | 12 (8–17) | 14 (9–17) | 16 (12–20) |
| Pediatric Logistic Organ Dysfunction score | 5 (4–8) | 6 (5–6) | 9 (5–12)a,b |
| Viral respiratory culture | |||
| Not performed | 7 (20.0) | 5 (14.7) | 0 |
| No virus | 3 (8.6) | 4 (11.8) | 3 (23.1) |
| Positive virus | 21 (60.0) | 21 (61.8) | 8 (61.5) |
| Positive multiple virus | 4 (11.4) | 4 (11.8) | 2 (15.4) |
| Bacterial respiratory culture | |||
| Not performed | 17 (48.6) | 4 (11.8) | 3 (23.1) |
| No bacteria | 1 (2.9) | 2 (5.9) | 0 |
| Positive bacteria or yeast | 17 (48.6) | 28 (82.4)a | 10 (76.9)a |
| Hours to sample collection | 17 (12–22) | 21 (11–37) | 23 (11–43) |
| Hospital days | 10 (7–13) | 16 (7–19) | 21 (15–38)a,b |
| PICU days | 7 (4–10) | 8 (6–13) | 15 (10–32)a,b |
| Ventilator days | 4 (2–6) | 5 (3–8)a | 7 (6–20)a,b |
| 28-d ventilator-free days | 25 (22–26) | 23 (19–24)a | 19 (5–22)a,b |
| Extracorporeal membranous oxygenation | 0 | 1 (2.9) | 5 (38.5)a,b |
| Died | 1 (2.9) | 1 (2.9) | 1 (7.7) |
PARDS = pediatric acute respiratory distress syndrome.
a
p < 0.05 vs at-risk.
b
p < 0.05 vs nonsevere.
Data are shown as the median (25–75th percentile) or the number of participants (n) (%).