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. 2022 Dec 20;6(Suppl 1):297. doi: 10.1093/geroni/igac059.1178

A LONGITUDINAL INCREASE IN SLEEP HEALTH PROBLEMS IN MIDDLE ADULTHOOD PREDICTS EARLY MORTALITY

Soomi Lee 1, Christina Mu 2, Meredith Wallace 3, Ross Andel 4, David Almeida 5, Orfeu Buxton 6, Sanjay Patel 7
PMCID: PMC9765943

Abstract

Negative consequences of sleep health problems are common in middle-age but poorly understood. This study investigated multidimensional sleep health in middle adulthood and mortality risk. Participants from the Midlife in the United States Study reported sleep characteristics in 2004-2006 (T1; n=9,640, Mage=52.72) and again in 2013-2016 (T2; n=4,334). Deaths since each survey were logged. Multidimensional sleep health composite captured Regularity, Satisfaction, Alertness, Efficiency, and Duration. Cox regression adjusted for sociodemographics and known risk factors (BMI, smoking, depression/anxiety, diabetes, and hypertension) indicated that each unit higher sleep health problems at T1 was associated with 245% and 324% increase in hazard rates for all-cause (Hazard Ratio; HR=3.45, p<.001) and heart disease (HR=4.24, p<.001) mortality, respectively. Those with an increase in sleep health problems at T2 compared to T1 had a 182% increase in all-cause mortality risk (HR=2.82, p<.05), but not heart disease mortality risk. Improving sleep health may reduce early mortality risk.


Articles from Innovation in Aging are provided here courtesy of Oxford University Press

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